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Acetyl-L-Carnitine

Autor admin | 21.08.2008 | Category Amino Acids

Acetylcarnitine (also known as l-acetylcarnitine and carnitine) is an important naturally-occurring nutrient responsible for production of energy and the vital brain chemical, acetylcholine. In various combinations, Acetyl-L-Carnitine can assist individuals with:

• Improved mental focus
• Enhanced concentration
• Appetite suppression
• Better sleep
• Vision support
• Healthier joints

Individuals who take Acetyl-L-Carnitine supplements notice a welcome increase in physical stamina, often within a few hours. Some notice an improvement in their moods as well. But the benefits don’t stop there. According to published studies, Acetyl-L-Carnitine benefits include:

• Decreased mental fatigue associated with chronic fatigue syndrome.
• Decreased physical fatigue in patients with multiple sclerosis
• Reduced alcohol-induced cellular organ damage
• Decreased depression in geriatric patients
• May assist individuals suffering from degenerative cerebellar ataxia
• Increased learning ability and enhanced memory
• Useful in chemotherapy induced peripheral neuropathy
• Improves mitochondrial function (involved in energy production.)
• Proven more effective than the drug tamoxifen in treating acute and early chronic
• Peyronie’s disease.
• Assists in reduction of neuronal death after peripheral nerve traumaImportant
• Alzheimer’s Disease Help

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Anti-Aging Benefits Too

Further, Acetyl-L-Carnitine may be a powerful anti-aging nutrient. Based on a study performed by scientists at the Division of Biochemistry and Molecular Biology, University of California, Berkeley, CA, scientists attempted to rejuvenate aging rats with a blend of lipoic acid and acetylcarnitine–two natural amino acids readily available in natural food stores. According to the study’s lead researcher, the results were incredible. The old rats became physically active, like much younger rats, with significantly improved memory.

Acetyl-L-Carnitine and alpha-lipoic acid are found within our cells and, when used together, positively impact mitochondria, which generate energy within the cells. Research has suggested the deterioration of mitochondria may be responsible for the aging process, probably because energy production creates destructive free radicals. Acetyl-L-Carnitine and alpha-lipoic acid together destroy free radicals within mitochondria.

Individuals who wish to take Acetyl-L-Carnitine and alpha-lipoic acid as supplements to receive the benefits of these powerful nutrients are cautioned to begin with small doses—perhaps 5 to 10 mg of lipoic acid and 30 to 100 mg of Acetyl-L-Carnitine. Most brands do not offer these nutrients in low doses, so it may be necessary to break open or cut the pill to achieve the lower dose.

Aids and Amino Acids

Autor admin | 20.08.2008 | Category Amino Acid News, Amino Acids Research, Amino Acids and Health Conditions

Aids patients suffer from sever loss of lean body mass. This loss of body tissue is caused from both protein and amino acid metabolism changing due to the advancement of the disease. Immunodeficiency syndrom (AIDS) and Amino acids have been studied for a while due to this waisting effect. A recent study narrows down which of the many amino acids are the ones could possibly be rate limiting as far as protein anabolism goes in patients with AIDS. 7 males who all have the aids virus were given an amino acid glucose mixture for a duration of 150 minutes. There was a control group of 8 healthy males hiv free. Threonine, methionine, isoleucine, histidine, tryptophan and leucine were tested prior to the infusion and it was noted that these amino acids were in much lower concentrations than that of the control group.

while the essential amino acids levels increased during the infusions in both the hiv patients and the control group, in the hiv patients the absolute increase was lower for the following amino acids valine, threonine, methionine and lysine. It was concluded that the two amino acids methionine and threonine were rate limiting when it comes to protein anabolism in HIV Patients.
Limiting amino acids in AIDS patients
Nutrition Research Newsletter, Sept, 1998

Alzheimer’s disease and Acetyl-L-Carnitine

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Autor admin | 19.08.2008 | Category Amino Acids and Health Conditions

Perhaps the most important benefit of Acetyl-L-Carnitine is its usefulness in halting the effects of Alzheimer’s disease and protecting against amyloid-beta neurotoxicity. While most of us are not familiar with this term, it refers to the molecular structure of Alzheimer’s disease in the human brain. The function of the amyloid protein is not yet clear, but it is currently though to be part of the development of neurons and, in Alzheimer’s patients, disease progression is affected by beta-amyloid proteins. According to a recent study, Acetyl-L-Carnitine acts as an “intracellular carrier”, protecting neurons and reducing attention deficits in Alzheimer’s patients. 23 patients who had not previously responded to treatment with acetylcholinesterase inhibitors were treated with low-dose Acetyl-L-Carnitine and evaluated for cognitive function, functional status and behavioral symptoms. The response rate was 38% after treatment, an increase of 50%, indicating Acetyl-L-Carnitine might be useful as a therapeutic option in Alzheimer’s patients.  

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Autor admin | 08.08.2008 | Category Amino Acid News

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Tyrosine

Autor admin | 20.07.2008 | Category Amino Acids

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Tyrosine helps regulate mood, stimulates the nervous system, can speed up metabolism and is used to treat conditions characterized by chronic fatigue. The body needs adequate supplies of tyrosine to make important brain chemicals that regulate appetite, pain sensitivity, and the body’s response to stress. It is also needed for normal functioning of the thyroid, pituitary, and adrenal glands—deficiency may lead to hypothyroidism, low blood pressure, chronic fatigue, and a sluggish metabolism.

Tyrosine is the precursor to melanin. A number of studies have found tyrosine to be useful during conditions of stress, cold, fatigue, prolonged periods of work or sleep deprivation. Tyrosine does not seem to have any significant effect on mood, cognitive ability, or physical performance in normal circumstances.

Tyrosine is available in almonds, avocados, bananas, dairy, beans and seeds. For sufferers of phenylketonuria, tyrosine is an essential amino acid, and supplementation is necessary. Tyrosine is available in powder form as well as in capsules, and is best taken at bedtime so that it does not compete for absorption with other amino acids.

Taurine

Autor admin | 20.07.2008 | Category Amino Acids

Taurine is a sulfur-containing amino acid manufactured in the body to help regulate the nervous system and muscles and keep the brain and heart healthy.

Taurine helps move potassium, magnesium, and sodium, around the body—three nutrients key to brain and heart function. Known to provide support for neurotransmitters and to have a protective effect on the human brain, some studies show taurine supplements strengthen the heart muscle and may prevent heart failure and arrhythmias.

In recent years, taurine has become a common ingredient in energy drinks. Taurine is used in combination with performance enhancing substances such as creatine and anabolic steroids, partly due to recent findings in mice that taurine alleviates muscle fatigue in strenuous workouts, raising exercise capacity.

Serine

Autor admin | 20.07.2008 | Category Amino Acids

Serine is central to the production of the myelin sheath that protects nerve cells as they speed nerve impulses through the brain and spinal cord. Deficiencies cause interference in the nerve impulses that supply information to and from the brain.

Serine also plays a role in the production of tryptophan, an amino acid that aids in the production of serotonin. Deficiencies in serotonin and tryptophan have been associated with depression, insomnia, confusion and anxiety, chronic fatigue syndrome and fibromyalgia.

The successful metabolism of serine requires sufficient amounts of vitamin B3, vitamin B6 and folic acid. Dietary sources of serine include meat and soy-based foods, dairy products, wheat gluten and peanuts.

Serine supplementation is available in capsule, tablet, and powder forms. It can be purchased as a stand-alone supplement or, more commonly, in combination amino acid supplements and sports drinks. Serine is often included as a natural moisturizing agent in many cosmetics and skin care preparations.

Proline

Autor admin | 20.07.2008 | Category Amino Acids

Proline is a non-essential amino acid partly responsible for the production of the collagen and cartilage that keep muscles and joints flexible. Proline helps give skin its youthful elasticity and reduces wrinkling and sagging associated with UV exposure and the normal aging of skin.

Healthy people produce sufficient amounts of praline; however, proline supplements may be beneficial for osteoarthritis and chronic back pain. Many sports and energy drinks include proline as a supplemental ingredient. Natural food sources of proline include meat, dairy and eggs.

Proline supplements are available in capsule and tablet form, often included in supplements marketed for the treatment of herpes, arthritis, and back pain. Proline supplements promoting cardiovascular health usually appear in combination with vitamin C, the recommended dose being 500 and 1,000 milligrams daily

People with liver or kidney disease should not take proline without first consulting a physician.

Ornithine

Autor admin | 20.07.2008 | Category Amino Acids

Since ornithine is a non-essential amino acid, readily produced by the body, deficiencies are rare. Occasionally, rapid growth, pregnancy, or a severe case of trauma or malnutrition can lead to ornithine deficiency. Dietary sources of ornithine include meat, fish, dairy products and eggs.

Ornithine serves several important functions within the body. It has been shown to increase liver function in people suffering from cirrhosis of the liver, and allows for the disposal of excess nitrogen through the urine.

Ornithine is also associated with muscle growth and repair. In aging adults, ornithine has been shown to slow the decay of muscle tissue that normally accompanies getting older. Part of this effect has to do with ornithine’s importance in synthesizing other amino acids. Proper balance within the body is important, and ornithine helps keep citrulline, proline, and glutamic acid at proper levels.

Glycine

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Autor admin | 20.07.2008 | Category Amino Acids

Glycine is a non-essential amino acid used to help create muscle tissue and convert glucose into energy. Also essential in maintaining healthy central nervous and digestive systems, glycine has been shown to provide protection from some types of cancer.

Glycine helps prevent the breakdown of muscle by boosting the body’s levels of creatine, an ahtlete’s commonly used supplement that helps build muscle mass.

Nearly one third of collagen, which keeps the skin and connective tissue firm and flexible, is composed of glycine. In this capacity, glycine makes the repair of damaged tissues possible whether by UV rays or physical wounding.

Glycine helps supply the body with the glucose needed for energy. It helps regulate blood sugar levels, and may be useful for treating low energy symptoms and fatigue, such as hypoglycemia, anemia, and Chronic Fatigue Syndrome. Glycine is also essential for a healthy digestive system.